WebTAFRO syndrome is a newly recognized variant of idiopathic multicentric Castleman disease (iMCD) that involves a constellation of syndromes: thrombocytopenia (T), anasarca (A), … WebDec 1, 2024 · In conclusion, we reported a case of TAFRO syndrome. Examination of renal histology revealed TMA-like glomerulopathy similar to renal findings in POEMS syndrome [8]. Tocilizumab was effective for anasarca, renal dysfunction, and systemic inflammation, but was not effective for thrombocytopenia, and PA-IgG was elevated.
Acute Kidney Injury Caused by TAFRO Syndrome in a Chinese …
WebJun 28, 2024 · Review of Literature: 19 iMCD patients with TAFRO syndrome had undergone a renal biopsy: 8 cases with author's diagnosis consistent with MPGN-like and 11 cases of … WebTAFRO syndrome is an extremely rare form of idiopathic MCD, characterized by thrombocytopenia, anasarca, fever, reticulin fibrosis on bone marrow biopsy, and organomegaly. ... -like injury and thrombotic microangiopathy (TMA) are the most reported histopathologic findings of renal biopsy. Several molecular mechanisms have been … harbinger ship location
Histopathologic findings of TAFRO syndrome with ... - ScienceDirect
WebMay 15, 2024 · However, there have been few reports about renal injury in a patient with TAFRO syndrome, and the pathogenesis of renal injury has remained unknown. Here, we present a case report about a patient with TAFRO syndrome who underwent kidney biopsy, which revealed thrombotic microangiopathy (TMA)-like pathological findings. WebSep 22, 2024 · TAFRO syndrome is a newly recognized disease entity characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis, renal dysfunction, and organomegaly. The objective of this study was to investigate the effectiveness of tocilizumab, an anti-interleukin-6 receptor antibody, in patients with TAFRO syndrome. We … WebJan 6, 2024 · TAFRO syndrome is a rare clinical subtype of idiopathic multicentric Castlemans disease characterised by thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly. Renal involvement is common, sometimes requiring temporary renal replacement therapy. Due to the associated thrombocytopenia, renal … harbinger shakespeare definition