Phf6-02
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Phf6-02
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WebNov 10, 2024 · Immunophenotyping, single-cell transcriptomic analyses and transplantation assays demonstrated markedly decreased accumulation of immunophenotypically defined HSCs, reduced myeloid bias and... WebMar 17, 2024 · Gan et al. show that PHF6 is a transcriptional repressor enriched in AgRP neurons and regulates immediate-early gene (IEG) expression. Depletion of PHF6 in AgRP neurons decreases hunger-driven feeding motivation and makes the mice resistant to body weight gain under repetitive fasting/refeeding conditions.
WebThe PHF6 gene in humans is also frequently mutated in human hematological malignancies, including T-cell acute lymphoblastic Leukemia (T-ALL) and Acute Myeloid Leukemia … WebItem # PHF6-02. PISCO PLASTIC PUSH-IN FITTING 6MM TUBE X 1/4" BSPT MALE/FEMALE UNIVERSAL ELBOW. $3.95 / EA Out of Stock; Contact for ETA; Log in to see if custom …
WebPMCID: PMC8807395 DOI: 10.1038/s41375-021-01392-1 Abstract T-cell acute lymphoblastic leukemia (T-ALL) is a malignant hematologic disease caused by gene mutations in T-cell progenitors. As an important epigenetic regulator, PHF6 mutations frequently coexist with JAK3 mutations in T-ALL patients. WebJul 26, 2024 · PHF6 Mutations in Hematologic Malignancies. Next generation sequencing has uncovered several genes with associated mutations in hematologic malignancies that …
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