Ef hand family
WebEvolution of the EF-Hand Family of Proteins Annual Review of Biophysics and Biomolecular Structure Vol. 23:473-507 (Volume publication date June 1994) … WebAn unusually short lifespan might indicate that your Ekhand ancestors lived in harsh conditions. A short lifespan might also indicate health problems that were once prevalent …
Ef hand family
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WebOct 21, 2024 · Calcium-binding EF-hand family protein; FUNCTIONS IN: calcium ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 … WebOct 15, 1999 · Background: The EF-hand family is a large set of Ca 2+-binding proteins that contain characteristic helix-loop-helix binding motifs that are highly conserved in sequence.Members of this family include parvalbumin and many prominent regulatory proteins such as calmodulin and troponin C. EF-hand proteins are involved in a variety …
WebMany calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand [1,2,3,4,5].This type of domain consists of a twelve residue loop flanked on both side by a twelve residue α-helical domain (see ). In an EF-hand loop the calcium ion is coordinated in a pentagonal … WebSince the delineation of the EF-hand motif in 1973, the family of EF-hand proteins has expanded to include at least 66 subfamilies thus far. EF-hand motifs are divided into two …
WebDec 1, 2000 · The EF-hand motif is the most common calcium-binding motif found in proteins. Several high-resolution structures containing different metal ions bound to EF-hand sites have given new insight into the modulation of their binding affinities. ... The thiol protease calpain is an interesting member of the EF-hand family, whose structure has … WebJan 1, 1989 · Abstract. The EF-hand homolog proteins bind calcium (Ca 2+) with dissociation constants in the micromolar range and are modulated by stimulus-induced increases in cytosolic free Ca 2+. We have grouped over 160 different EF-hand homolog proteins into ten subfamilies and ten unique categories. Except for troponin-C, all …
WebThe C2 domain is formed by eight β-strands which can bind two or three Ca 2+ -ions in the loop regions. In contrast, members of the EF-hand superfamily bind Ca 2+ through a well-characterized helix-loop-helix motif. With 250 identified members in the human genome, the EF-hand superfamily is the largest family of eukaryotic Ca 2+ -binding proteins.
WebOct 2, 2024 · cd00213 (PSSM ID: 238131): Conserved Protein Domain Family S-100, S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. ... Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins … motorcycle\u0027s 0wWebthe four EF-hands deserves a thorough investigation. Previous reports showed that the large family of EF-hand proteins likely arose from a founder protein with a single EF-hand in the most recent common ancestor of all extant eukary-otes (11, 14 –18). Different EF-hand containing proteins bind motorcycle\u0027s 2wWebJan 5, 2024 · SOS3 Calcium-binding EF-hand family protein [ (thale cress)] Gene ID: 832494, updated on 28-Aug-2024 Summary encodes a calcium sensor that is essential for K+ nutrition, K+/Na+ selectivity, and salt tolerance. motorcycle\\u0027s ywWebAug 31, 2024 · ALG-2 is a penta-EF-hand Ca2+-binding protein and interacts with a variety of proteins in mammalian cells. In order to find new ALG-2-binding partners, we searched a human protein database and retrieved sequences containing the previously identified ALG-2-binding motif type 2 (ABM-2). After selecting 12 high-scored sequences, we expressed … motorcycle\u0027s 4wWebJan 10, 2024 · We here show that the Ca 2+-binding EF-hand family protein ZmNSA1 confers transcriptional regulation of maize PM-H +-ATPase (Fig. 7), which acts at the … motorcycle\u0027s 3tWebCa2+-Binding Proteins of the EF-Hand Superfamily: Diagnostic and Prognostic Biomarkers and Novel Therapeutic Targets A multitude of Ca2+-sensor proteins containing the specific Ca2+-binding motif (helix-loop-helix, called EF-hand) are of major clinical relevance in a many human diseases. motorcycle\\u0027s 9wWeb该CETN3 Polyclonal Antibody. The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a … motorcycle\u0027s 3w