Charcot-Marie-Tooth disease (CMT) is one of a group of disorders that cause damage to the peripheral nerves—the nerves that … See more Diagnosing CMT Diagnosis begins with a detailed medical history, family history, and neurological examination. A physician will look for evidence of: 1. Muscle weakness in the arms, legs, hands, and feet 2. Decreased … See more CMT is caused by mutations in genes that support or produce proteins involved in the structure and function of either the peripheral nerve … See more Ongoing research on CMT includes efforts to identify more of the mutant genes and proteins that cause the various disease subtypes, discover the mechanisms of nerve degeneration and muscle atrophy with the goal of … See more WebCharcot-Marie-Tooth (CMT) disease is an inherited nerve problem. It causes abnormalities in the nerves that supply your feet, legs, hands, and arms. It affects both your motor and sensory nerves. Motor nerves carry signals from your brain to your muscles, telling them to …
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