WebReference genomes used were C. belfantii (FRC0043), C. diphtheriae bv. Gravis (NCTC 13129) and Mitis (ISS3319), ... Important variables such as country of origin, travel history, contact with animals, and vaccination status were not collected for most of the nontoxigenic isolates, as it is currently not mandatory based on national surveillance ... WebJun 1, 1995 · A non-toxigenic strain of C. diphtheriae var. gravis was responsible for an outbreak of infection in a boys residential school in 1975.19 It was isolated from seven of 19 boys with sore throats; and 24 asymptomatic carriers.
Infective Endocarditis Due to Nontoxigenic Corynebacterium …
C. diphtheriae is an aerobic, gram-positive bacillus. Toxin production (toxigenicity) occurs only when the bacillus is itself infected (lysogenized) by specific viruses (corynebacteriophages) carrying the genetic information for the toxin (toxgene). Diphtheria toxin causes the local and systemic manifestations of … See more Susceptible persons may acquire toxigenic diphtheria bacilli in the nasopharynx. The organism produces a toxin that inhibits cellular protein … See more The incubation period for diphtheria is 2 to 5 days, with a range of 1 to 10 days. Disease can involve almost any mucous membrane. In … See more During the 1920s, 100,000 to 200,000 cases of diphtheria (140 to 150 cases per 100,000 population) and 13,000 to 15,000 deaths were reported … See more Corynebacterium diphtheriae is the pathogenic bacterium that causes diphtheria. It is also known as the Klebs–Löffler bacillus, because it was discovered in 1884 by German bacteriologists Edwin Klebs (1834–1912) and Friedrich Löffler (1852–1915). The bacteria are usually harmless unless they are infected by a bacteriophage that carries a gene that gives rise to a toxin. This toxin causes th… hotels in penguin tasmania
Editorial: Diphtheria - the Australian perspective
WebNational Center for Biotechnology Information WebAll of the isolates were identified as non-toxigenic C. diphtheriae var gravis. Sporadic cases of endocarditis due to C. diphtheriae have rarely been reported; septic arthritis complicating endocarditis due to this organism has not previously been described. WebFeb 1, 2000 · The specimen contained C. diphtheriae var. gravis (toxigenic), Streptococcus mitis, and Neisseria species. Only 30 laboratories (9%) performed toxigenicity tests. The remainder (81%) correctly identified the organism but did not perform toxigenicity tests; they all referred the isolate to the Reference Laboratory. felohabo